Cromolyn

Cromolyn

SCHEMBL318268

O=C(O)c1cc(=O)c2c(OCC(O)COc3cccc4oc(C(=O)O)cc(=O)c34)cccc2o1.[NaH].[NaH]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 3/20 0.97
▸ LMNA P02545 1/20 0.97
▸ TDP1 Q9NUW8 1/20 0.97
▸ MEN1 O00255 3/20 0.76
▸ KMT2A Q03164 3/20 0.76
▸ HIF1A Q16665 1/20 0.76
▸ ABCG2 Q9UNQ0 9/20 0.47
▸ ABCB1 P08183 2/20 0.47
▸ KDM4E B2RXH2 2/20 0.47
▸ USP2 O75604 2/20 0.47
▸ CSNK2A2 P19784 1/20 0.47
▸ PTGS1 P23219 1/20 0.47
▸ CSNK2B P67870 1/20 0.47
▸ CSNK2A1 P68400 1/20 0.47
▸ CSNK2A3 Q8NEV1 1/20 0.47
▸ BCHE P06276 1/20 0.46
▸ ACHE P22303 1/20 0.46
▸ ADRB2 P07550 2/20 0.43
▸ NMT2 O60551 1/20 0.43
▸ ADRB1 P08588 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cromolyn SCHEMBL8199 1.00 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL29353205 0.99 GPR35 (1.00) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL3865 0.99 GPR35 (1.00) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL29352570 0.99 GPR35 (1.00) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL8662365 0.97 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL4108171 0.97 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11253121 0.95 GPR35 (0.93) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11832140 0.93 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11175797 0.93 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A
SCHEMBL2717434 0.93 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117760980-B Glucose detection method based on lyotropic liquid crystal liquid drops 南京邮电大学 2026-05-15 — — CN claimed
CN-117760980-A Glucose detection method based on lyotropic liquid crystal liquid drops 南京邮电大学 2024-03-26 — — CN claimed
CN-116889562-A Macrophage/microglial cell in neuroinflammation related to neurodegenerative diseases 通用医疗公司 2023-10-17 — — CN claimed
CN-116782865-A Atomic layer deposition coated pharmaceutical packages, improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines SIO2医药产品公司 2023-09-19 — — CN claimed
US-20220235270-A1 DEFECT MEDIATED LYOTROPIC NEMATIC GEL THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2022-07-28 — — US claimed
EP-3986979-A1 DEFECT MEDIATED LYOTROPIC NEMATIC GEL The University Court Of The University of Edinburgh (GB) 2022-04-27 — — EP claimed
CN-113292644-A Cytokine activity stabilizer and preparation method thereof 南京艾拓生命科技有限公司 2021-08-24 — — CN claimed
CN-112274479-A Hair growing method based on hair mother stem cells and microneedles 弘康信达(江苏)医学研究有限公司 2021-01-29 — — CN claimed
WO-2020254813-A1 DEFECT MEDIATED LYOTROPIC NEMATIC GEL THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2020-12-24 — — WO claimed
US-20190240194-A1 MACROPHAGES/MICROGLIA IN NEURO-INFLAMMATION ASSOCIATED WITH NEURODEGENERATIVE DISEASES THE GENERAL HOSPITAL CORPORATION 2019-08-08 — — US claimed
US-6684405-B2 PROTECTIVE DEVICES COMPRISING ELASTOMERS HAVING COATING MIXTURES OF CROMOLYN'S, ENZYME INHIBITORS SELECTED FROM ANTITRYPSIN, MACROBLOBULIN OR SECRETORY LEUCOCYTE PROTEASE INHIBITORS AS VIRICIDES AND ANTIALLERGENS LEZDEY JOHN (US) 2004-02-03 — — US claimed
EP-1322595-A2 (5-(2-HYDROXY-4-CHLOROBENZOYL) AMINOVALERIC ACID AND SALTS THEREOF AND COMPOSITIONS CONTAINING THE SAME FOR DELIVERING ACTIVE AGENTS Emisphere Technologies, Inc. (US) 2003-07-02 — — EP claimed
US-6573249-B2 A formulation for healing burns and wounds in mammals, which contains a cromolyn sodium or disodium salt or the combination of cromolyn salt and hyaluronic acid in suitable carrier ALPHAMED PHARMACEUTICAL CORP. 2003-06-03 — — US claimed
US-6511960-B2 Cromolyn for eye and ear infections ALPHAMED PHARMACEUTICALS CORP 2003-01-28 — — US claimed
US-20020189001-A1 Surgical and examination gloves LEZDEY JOHN (US) 2002-12-19 — — US claimed
US-6468557-B1 HERPES SIMPLEX VIRUS (HSV) OR HUMAN PAPILLOMA VIRUS (HPV); CROMOLYN COMPOUND ALPHAMED PHARMACEUTICAL CORP. 2002-10-22 — — US claimed
US-20020091100-A1 Cromolyn for eye and ear infections ALPHAMED PHARMACEUTICALS CORPORATION 2002-07-11 — — US claimed
US-6379684-B1 Cosmetic compositions containing cromolyn compounds for revitalizing the skin ALPHAMED PHARACEUTICAL CORP. 2002-04-30 — — US claimed
WO-2002019969-A2 (5-(2-HYDROXY-4-CHLOROBENZOYL) AMINOVALERIC ACID AND SALTS THEREOF AND COMPOSITIONS CONTAINING THE SAME FOR DELIVERING ACTIVE AGENTS EMISPHERE TECHNOLOGIES INC. (US) 2002-03-14 — — WO claimed
US-20010041684-A1 Topical wound therapeutic compositions LEZDEY JOHN (US) 2001-11-15 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240194-A1 MACROPHAGES/MICROGLIA IN NEURO-INFLAMMATION ASSOCIATED WITH NEURODEGENERATIVE DISEASES CD68, PRNP, HTT GPR35 1528/4885LMNA 755/4885TDP1 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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