Cromolyn

Cromolyn

SCHEMBL29353205

O=C(O)c1cc(=O)c2c(OCC(O)COc3cccc4oc(C(=O)O)cc(=O)c34)cccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR35 Q9HC97 3/20 1.00
▸ LMNA P02545 1/20 1.00
▸ TDP1 Q9NUW8 1/20 1.00
▸ MEN1 O00255 3/20 0.77
▸ KMT2A Q03164 3/20 0.77
▸ HIF1A Q16665 1/20 0.77
▸ KDM4E B2RXH2 2/20 0.48
▸ USP2 O75604 2/20 0.48
▸ CSNK2A2 P19784 1/20 0.48
▸ PTGS1 P23219 1/20 0.48
▸ CSNK2B P67870 1/20 0.48
▸ CSNK2A1 P68400 1/20 0.48
▸ CSNK2A3 Q8NEV1 1/20 0.48
▸ ABCG2 Q9UNQ0 9/20 0.47
▸ ABCB1 P08183 2/20 0.47
▸ BCHE P06276 1/20 0.46
▸ ACHE P22303 1/20 0.46
▸ ADRB2 P07550 2/20 0.43
▸ NMT2 O60551 1/20 0.43
▸ ADRB1 P08588 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cromolyn SCHEMBL3865 1.00 GPR35 (1.00) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL29352570 1.00 GPR35 (1.00) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL8662365 0.99 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL4108171 0.99 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL318268 0.99 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
Cromolyn SCHEMBL8199 0.99 GPR35 (0.97) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11253121 0.96 GPR35 (0.93) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11832140 0.94 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A
SCHEMBL11175797 0.94 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A
SCHEMBL2717434 0.94 GPR35 (0.88) GPR35LMNATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 975 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 — — EP claimed
EP-4434588-B1 AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2026-04-08 — — EP claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 — — US claimed
EP-4058037-B1 FIBROBLAST-BASED THERAPY FOR TREATMENT AND PREVENTION OF STROKE SPINALCYTE LLC (US) 2026-01-28 — — EP claimed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP claimed
WO-2025137230-A1 USE OF DEXPRAMIPEXOLE FOR THE TREATMENT OF INADEQUATELY CONTROLLED MODERATE TO SEVERE ASTHMA ARETEIA THERAPEUTICS, INC. (US) 2025-06-26 — — WO claimed
US-12337065-B2 Compositions for treating viral infections and methods for same ACCESS TO ADVANCED HEALTH INSTITUTE (US) 2025-06-24 — — US claimed
WO-2025128784-A1 METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE SEN-JAM PHARMACEUTICAL INC. (US) 2025-06-19 — — WO claimed
EP-4302829-B1 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION STEALTH BIOTHERAPEUTICS INC (US) 2025-05-21 — — EP claimed
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 — — US claimed
WO-2023069255-A1 METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-27 — — WO claimed
WO-2023069549-A1 METHODS AND COMPOSITIONS COMPRISING PEPTIDOMIMITICS FOR TREATING, PREVENTING, INHIBITING, AMELIORATING OR DELAYING THE ONSET OF OPHTHALMIC CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-27 — — WO claimed
US-11612633-B2 Methods and compositions for preventing or treating ophthalmic conditions STEALTH BIOTHERAPEUTICS INC. (US) 2023-03-28 — — US claimed
US-11602603-B2 Nasal delivery devices Optinose, Inc. (US) 2023-03-14 — — US claimed
US-20220387408-A1 USE OF MAST CELL STABILIZER FOR THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION INST NAT SANTE RECH MED (FR) 2022-12-08 — — US claimed
EP-4058010-A1 USE OF MAST CELL STABILIZER FOR THE TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2022-09-21 — — EP claimed
WO-2022192252-A1 USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY CHRONIC AIRWAY THERAPEUTICS LIMITED (AU) 2022-09-15 — — WO claimed
US-20220265670-A1 COMPOSITION AND USE THEREOF FOR THE TREATMENT OF CUTANEOUS MASTOCYTOSIS AC BIOSCIENCE SA (CH) 2022-08-25 — — US claimed
EP-3972574-A1 COMPOSITION AND USE THEREOF FOR THE TREATMENT OF CUTANEOUS MASTOCYTOSIS AC BioScience SA (CH) 2022-03-30 — — EP claimed
US-20220031980-A1 NASAL DELIVERY DEVICES OAKTREE FUND ADMINISTRATION, LLC 2022-02-03 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS NR2E3, ALDH1A2, PDE6D GPR35 3784/4885LMNA 27/4885TDP1 434/4885
US-20220265670-A1 COMPOSITION AND USE THEREOF FOR THE TREATMENT OF CUTANEOUS MASTOCYTOSIS CPA3, KIT, CMA1 GPR35 454/4885LMNA 2081/4885TDP1 3196/4885
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases GHSR, GIPR, GHRHR GPR35 103/4885LMNA 4606/4885TDP1 4590/4885
US-11612633-B2 Methods and compositions for preventing or treating ophthalmic conditions CRYAA, CRYAB, IAPP GPR35 1288/4885LMNA 1439/4885TDP1 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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