Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745577 | 0.93 | TSHR (0.44) | MAPK1TSHRABCB11TNFSF11NR3C1 | |
| SCHEMBL318040 | 0.87 | TSHR (0.45) | MAPK1TSHRABCB11TNFSF11NR3C1 | |
| SCHEMBL318039 | 0.80 | TSHR (0.49) | MAPK1TSHRTNFSF11NR3C1KDM4E | |
| SCHEMBL151821 | 0.79 | TSHR (0.55) | MAPK1TSHRTNFSF11NR3C1KDM4E | |
| SCHEMBL43785 | 0.78 | MAPK1 (0.61) | MAPK1TSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL29385313 | 0.78 | MAPK1 (0.61) | MAPK1TSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL24195886 | 0.77 | KDM4E (0.47) | MAPK1TSHRTNFSF11NR3C1KDM4E | |
| Acetic Acid SCHEMBL28559644 | 0.75 | MAPK1 (0.62) | MAPK1TSHRKDM4EALDH1A1CYP2C9 | |
| Potassium Ion SCHEMBL27764600 | 0.75 | MAPK1 (0.57) | MAPK1TSHRKDM4EALDH1A1CYP2C9 | |
| SCHEMBL3211185 | 0.75 | MAPK1 (0.35) | MAPK1TSHRKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093405-B2 | Formation of 18F and 19F fluoroarenes bearing reactive functionalities | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2012-01-10 | — | — | US | disclosed |
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | RARB, RARG, RARA | MAPK1 1701/4885TSHR 51/4885ABCB11 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.