Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385313 | 1.00 | MAPK1 (0.61) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| Acetic Acid SCHEMBL28559644 | 0.96 | MAPK1 (0.62) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| Potassium Ion SCHEMBL27764600 | 0.96 | MAPK1 (0.57) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| SCHEMBL19047101 | 0.88 | KDM4E (0.48) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| Benzamide SCHEMBL1114683 | 0.86 | MAPK1 (0.51) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| SCHEMBL5212814 | 0.86 | MAPK1 (0.71) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| SCHEMBL8897061 | 0.85 | MAPK1 (0.50) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| SCHEMBL6693607 | 0.82 | MAPK1 (0.49) | MAPK1PTPN1KDM4EALDH1A1BLM | |
| SCHEMBL31604474 | 0.82 | PTGS2 (0.57) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL177166 | 0.82 | PTGS2 (0.57) | MAPK1KDM4EALDH1A1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4756 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637469-B2 | 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2026-05-26 | — | — | US | claimed |
| CN-116813686-B | Asymmetric synthesis method and application of 7-oxo-resorcinol lactone | 欣凯医药化工中间体（上海）有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-12590049-B2 | Metal-free oxidation of pyrenes | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-03-31 | — | — | US | claimed |
| US-20260034125-A1 | N-PHENYL-1-(PHENYLSULFONYL)PIPERIDIN-4-AMINE DERIVATIVES AS CCR6 INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2026-02-05 | — | — | US | claimed |
| EP-4661964-A1 | COMPOUNDS AS CCR6 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-12-17 | — | — | EP | claimed |
| US-20250353859-A1 | COMPOUNDS AS CCR6 INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2025-11-20 | — | — | US | claimed |
| EP-4630402-A1 | SULFONYL DERIVATIVES AS CCR6 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-10-15 | — | — | EP | claimed |
| EP-4626866-A1 | NOVEL TRILACICLIB INTERMEDIATES, METHOD OF PREPARATION AND USE THEREOF | Assia Chemical Industries Ltd. (IL) | 2025-10-08 | — | — | EP | claimed |
| EP-4601744-A1 | NEW COMPOUNDS, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS DRUGS | B&A Oncomedical (FR) | 2025-08-20 | — | — | EP | claimed |
| US-20250197439-A1 | DECARBOXYLATIVE ACETOXYLATION USING MN(II) OR MN(III) REAGENT FOR SYNTHESIS OF 4'-ACETOXY-NUCLEOSIDE AND USE THEREOF FOR SYNTHESIS OF CORRESPONDING 4'-(DIMETHOXYPHOSPHORYL)METHOXY-NUCLEOTIDE | DICERNA PHARMACEUTICALS, INC. (US) | 2025-06-19 | — | — | US | claimed |
| WO-2002096898-A2 | PROCESS FOR THE PREPARATION OF PROSTAGLANDINS AND ANALOGUES THEREOF | RESOLUTION CHEMICALS LIMITED (GB) | 2002-12-05 | — | — | WO | claimed |
| WO-2002022646-A9 | METHOD FOR THE PREPARATION OF 21-HYDROXY-6,19-OXIDOPROGESTERONE (21OH-6OP) | APPLIED RESEARCH SYSTEMS (NL) | 2002-09-19 | — | — | WO | claimed |
| US-6399776-B2 | Processes and intermediates in the synthesis of 5-(3-exo-bicyclo[2.2.1]hept-2-yloxy-4-methoxyphenyl)-3,4,5,6-tetrahydropyrimidine-2(1H)-one | PFIZER INC | 2002-06-04 | — | — | US | claimed |
| WO-2002022646-A2 | METHOD FOR THE PREPARATION OF 21-HYDROXY-6,19-OXIDOPROGESTERONE (21OH-6OP) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-03-21 | — | — | WO | claimed |
| US-20010041798-A1 | Processes and intermediates in the synthesis of 5-(3-{exo-bicyclo{2.2.1}hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6- tetrahydropyrimidin-2(1H)-one | LACOUR THOMAS G (US) | 2001-11-15 | — | — | US | claimed |
| US-5703230-A | Meso-monoiodo-substituted tetramacrocyclic compounds and methods for making and using the same | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-12-30 | — | — | US | claimed |
| EP-0794954-A1 | MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | QUADRA LOGIC TECHNOLOGIES INC. (CA) | 1997-09-17 | — | — | EP | claimed |
| EP-0775119-A1 | PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3- EXO-BICYCLO 2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE | PFIZER INC. (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1996016966-A1 | MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | QUADRA LOGIC TECHNOLOGIES, INC. (CA) | 1996-06-06 | — | — | WO | claimed |
| WO-1996004253-A1 | PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3-[EXO-BICYCLO[2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE | PFIZER INC. (US) | 1996-02-15 | — | — | WO | claimed |