Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184235 | 0.81 | SMN1; SMN2 (0.42) | PDE4BSMN1; SMN2KCNH2TP53KDM4E | |
| SCHEMBL1138640 | 0.78 | PDE4B (0.53) | PDE4BSMN1; SMN2KCNH2TP53KDM4E | |
| SCHEMBL1138512 | 0.74 | ALDH1A1 (0.37) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL1138033 | 0.72 | PDE4B (0.53) | PDE4BSMN1; SMN2KCNH2ALDH1A1MEN1 | |
| SCHEMBL447506 | 0.70 | KDM4E (0.42) | TP53KDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL5043172 | 0.69 | POLB (0.60) | SMN1; SMN2TP53KDM4ETSHRALDH1A1 | |
| SCHEMBL2479793 | 0.68 | MAPT (0.53) | SMN1; SMN2TP53KDM4ETSHRALDH1A1 | |
| SCHEMBL1138693 | 0.68 | MEN1 (0.39) | TP53KDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL30406784 | 0.67 | MAPT (0.51) | SMN1; SMN2TP53KDM4ETSHRALDH1A1 | |
| SCHEMBL26908045 | 0.67 | MAPT (0.51) | SMN1; SMN2TP53KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652000-B2 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2010-01-26 | — | — | US | disclosed |
| US-20060009422-A1 | Boron-containing compounds and methods of use | ANACOR PHARMACEUTICALS, INC. | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009422-A1 | Boron-containing compounds and methods of use | BROX, BTD, PBDC1 | PDE4B 4059/4885SMN1; SMN2 4705/4885KCNH2 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.