Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184691 | 1.00 | GPR119 (0.50) | GPR119KDM2B | |
| SCHEMBL3181205 | 0.92 | GPR119 (0.51) | GPR119KDM2B | |
| SCHEMBL3181200 | 0.92 | GPR119 (0.51) | GPR119KDM2B | |
| SCHEMBL3186658 | 0.90 | KDM2B (0.44) | GPR119KDM2B | |
| SCHEMBL3186668 | 0.90 | KDM2B (0.44) | GPR119KDM2B | |
| SCHEMBL4553944 | 0.88 | GPR119 (0.54) | GPR119KDM2B | |
| SCHEMBL4439148 | 0.88 | KDM2B (0.42) | GPR119KDM2B | |
| SCHEMBL3182548 | 0.81 | GPR119 (0.65) | GPR119 | |
| SCHEMBL3180730 | 0.81 | GPR119 (0.64) | GPR119 | |
| SCHEMBL3184507 | 0.81 | KDM2B (0.46) | GPR119KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-28 | — | — | US | claimed |
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GCGR, GPR65 | GPR119 1/4885KDM2B 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.