Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185002 | 1.00 | NPC1 (0.45) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3192196 | 0.85 | PPARG (0.41) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3192190 | 0.85 | PPARG (0.41) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL16693333 | 0.82 | MAPT (0.54) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3197447 | 0.78 | GSTA1 (0.40) | NPC1RAB9AMAPTL3MBTL1MEN1 | |
| SCHEMBL3197451 | 0.78 | GSTA1 (0.40) | NPC1RAB9AMAPTL3MBTL1MEN1 | |
| SCHEMBL13269903 | 0.78 | KMT2A (0.38) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3194460 | 0.78 | ALDH1A1 (0.39) | NPC1RAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3188163 | 0.78 | PPARG (0.39) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL3188158 | 0.78 | PPARG (0.39) | MAPTMEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867683-B1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7662937-B2 | Polymerizable dye and ophthalmic lens containing the same | MENICON CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090082553-A1 | Novel Polymerizable Dye and Ophthalmic Lens Containing the Same | MENICON CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1867683-A1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO., LTD. (JP) | 2007-12-19 | — | — | EP | disclosed |