⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911003 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1432350 | 0.98 | GABRP (0.53) | — | |
| SCHEMBL25054208 | 0.81 | GABRP (0.52) | — | |
| Hydrochloric Acid SCHEMBL23201156 | 0.79 | GABRP (0.50) | — | |
| SCHEMBL5343427 | 0.78 | — | — | |
| SCHEMBL642783 | 0.78 | — | — | |
| SCHEMBL17058360 | 0.78 | — | — | |
| SCHEMBL11888555 | 0.78 | — | — | |
| SCHEMBL14425020 | 0.78 | — | — | |
| SCHEMBL312816 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011048-A | Preparation method and application of polyvinyl chloride antibacterial composite material | 广东亮丰达实业有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-107337634-B | A kind of preparation method of Abbe Seeley midbody compound | 新发药业有限公司 | 2019-07-09 | — | — | CN | claimed |
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |
| CN-101495464-B | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2014-03-05 | — | — | CN | claimed |
| CN-103396398-A | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2013-11-20 | — | — | CN | claimed |
| EP-2585069-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | Janssen Pharmaceutica, N.V. (BE) | 2013-05-01 | — | — | EP | claimed |
| EP-1973886-B1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2013-02-27 | — | — | EP | claimed |
| WO-2012006004-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-12 | — | — | WO | claimed |
| US-20110319400-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA, NV (BE) | 2011-12-29 | — | — | US | claimed |
| EP-2385042-A1 | Prokineticin 1 receptor antagonists | Janssen Pharmaceutica N.V. (BE) | 2011-11-09 | — | — | EP | claimed |
| WO-2007079214-A2 | PROKINETICIN 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-12 | — | — | WO | claimed |
| EP-1362054-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064599-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |
| EP-0934064-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-01-09 | — | — | EP | claimed |
| EP-0934064-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017274-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1998-04-30 | — | — | WO | claimed |
| EP-0607804-B1 | Process for the preparation of 2-amino-5-aminomethylpyridine | BAYER AG (DE) | 1996-07-10 | — | — | EP | claimed |
| US-5478944-A | Process for the preparation of 2-amino-5-aminomethyl-pyridine | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-26 | — | — | US | claimed |
| EP-0658162-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 1995-06-21 | — | — | EP | claimed |
| EP-0607804-A1 | Process for the preparation of 2-amino-5-aminomethylpyridine | BAYER AG (DE) | 1994-07-27 | — | — | EP | claimed |