SCHEMBL312816

SCHEMBL312816

CCc1ccc(N)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30279718 1.00
SCHEMBL10264595 0.85 SMN1; SMN2 (0.58)
SCHEMBL13484223 0.83 PIK3CD (0.52)
SCHEMBL294092 0.82 GABRP (0.50)
SCHEMBL4154226 0.79 NFKB1 (0.54)
SCHEMBL29911003 0.78
SCHEMBL318570 0.78
SCHEMBL14535423 0.77 GABRP (0.46)
SCHEMBL10723761 0.77 RAB9A (0.54)
SCHEMBL1126370 0.77 HRH3 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN claimed
EP-2262501-A2 TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS Solanan, Inc. (US) 2010-12-22 EP claimed
WO-2009111785-A2 TREATMENT OF SEPSIS WITH 5-ETHYL-1-PHENYL-2(1H)-PYRIDONE AND NOVEL METHODS FOR SYNTHESIS SOLANAN, INC. (US) 2009-09-11 WO claimed
WO-2003013523-A1 SH3 PROTEIN DOMAINS AND THEIR LIGANDS ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) 2003-02-20 WO claimed
US-5972975-A Substituted 2-aminopyridines as inhibitors of nitric oxide synthase MERCK & CO., INC. (US) 1999-10-26 US claimed
US-12384773-B2 Thiazole compounds and methods of use thereof ARCUS BIOSCIENCES, INC. (US) 2025-08-12 US disclosed
WO-2025096979-A1 THIAZOLE COMPOUNDS AS KIT INHIBITORS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2025-05-08 WO disclosed
US-20250145606-A1 THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF ARCUS BIOSCIENCES, INC. (US) 2025-05-08 US disclosed
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN disclosed
US-20240239764-A1 SUBSTITUTED AMINOBENZYL HETEROARYL COMPOUNDS AS EGFR AND/OR PI3K INHIBITORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-07-18 US disclosed
US-12030853-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2024-07-09 US disclosed
CN-117800904-A ROR gamma inhibitors containing sulfonyl structures 正大天晴药业集团股份有限公司 2024-04-02 CN disclosed
EP-0333185-A2 Cyan dye-forming coupler and silver halide photosensitive material containing the same FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed
US-4619997-A Substituted 2-pyridylmethylthio and sulfinyl-benzimidazoles as gastric antisecretory agents THE UPJOHN COMPANY (US) 1986-10-28 US disclosed
US-4575554-A CYTOPROTECTIVE THE UPJOHN COMPANY (US) 1986-03-11 US disclosed
EP-0098684-A2 Modified chichibabin reaction, and novel pyridine derivatives REILLY INDUSTRIES, INC. (US) 1984-01-18 EP disclosed
US-4386209-A Chichibabin reaction REILLY TAR & CHEMICAL CORPORATION (US) 1983-05-31 US disclosed
US-4192944-A ANTIANAPHYLACTIC BRISTOL-MYERS COMPANY (US) 1980-03-11 US disclosed
US-4122274-A ANTIALLERGY BRISTOL-MYERS COMPANY (US) 1978-10-24 US disclosed
US-4039550-A ANTHELMINTIC AGENTS STERLING DRUG INC. (US) 1977-08-02 US disclosed