Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.75 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.75 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.75 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.75 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.75 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.75 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.61 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.53 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30456647 | 1.00 | GRIN2D (0.75) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31495016 | 0.86 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL438374 | 0.86 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31268743 | 0.83 | GRIN2D (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8872530 | 0.82 | GRIN2D (0.83) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Tert-Butyl Formate SCHEMBL28782895 | 0.81 | GRIN2D (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ethoxycarbonyl Group SCHEMBL27776820 | 0.80 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL18190511 | 0.80 | GRIA1 (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL404118 | 0.79 | PARP1 (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30013261 | 0.79 | PARP1 (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016099-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | TRINUERO (KR) | 2022-01-20 | — | — | US | claimed |
| WO-2020116742-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | 주식회사 트리뉴로 | 2020-06-11 | — | — | WO | claimed |
| US-8183409-B2 | High yield and rapid synthesis methods for producing metallo-organic salts | OSTEOLOGIX A/S (DK) | 2012-05-22 | — | — | US | claimed |
| US-20090291926-A1 | HIGH YIELD AND RAPID SYNTHESIS METHODS FOR PRODUCING METALLO-ORGANIC SALTS | CHRISTGAU STEPHAN | 2009-11-26 | — | — | US | claimed |
| US-20070282127-A1 | High Yield And Rapid Synthesis Methods For Producing Metallo-Organic Salts | OSTEOLOGIX A/S | 2007-12-06 | — | — | US | claimed |
| EP-1758652-A2 | IMPROVING PAIN TREATMENT WITH STRONTIUM COMBINATIONS | Osteologix A/S (DK) | 2007-03-07 | — | — | EP | claimed |
| EP-1744770-A2 | HIGH YIELD AND RAPID SYNTHESES METHODS FOR PRODUCING METALLO-ORGANIC SALTS | Osteologix A/S (DK) | 2007-01-24 | — | — | EP | claimed |
| WO-2005123192-A2 | IMPROVING PAIN TREATMENT WITH STRONTIUM COMBINATIONS | OSTEOLOGIX A/S (DK) | 2005-12-29 | — | — | WO | claimed |
| WO-2005108339-A2 | HIGH YIELD AND RAPID SYNTHESES METHODS FOR PRODUCING METALLO-ORGANIC SALTS | OSTEOLOGIX A/S (DK) | 2005-11-17 | — | — | WO | claimed |
| WO-2004039409-A2 | COMPOSITION COMPRISING ACTIVATORS OF IK POTASSIUM CHANNELS AND CALCINEURIN ANTAGONISTS AND USE THEREOF | SWITCH BIOTECH AG (DE) | 2004-05-13 | — | — | WO | claimed |
| CN-115246795-B | Isoxazoline compound containing ether structure at 4-phenyl para-position, preparation method thereof and application thereof as insecticidal and bactericidal agent | 瑞普（天津）生物药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11655222-B2 | Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors | ASTRAZENECA AB (SE) | 2023-05-23 | — | — | US | disclosed |
| US-20230025351-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | BIOPHARMA CREDIT PLC (GB) | 2023-01-26 | — | — | US | disclosed |
| CN-115246795-A | Isoxazoline compound with 4-phenyl para-position containing ether structure, preparation thereof and application thereof as insecticide and bactericide | 瑞普（天津）生物药业有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-113575590-B | Cultivation method for promoting gingko to bloom and bear fruits | 四川云辰园林科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| EP-0731380-A1 | Method for forming an image and silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |
| US-5003079-A | Phosgene, O-Phenylenediamine, Basic Catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| US-4367337-A | Process for conversion of benzimidazolones to benzotriazoles | THE SHERWIN-WILLIAMS COMPANY (US) | 1983-01-04 | — | — | US | disclosed |
| US-3943109-A | CURING | CIBA-GEIGY CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025351-A1 | CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS | DPP4, DPP7, DPEP1 | GRIN2D 3407/4885GRIN3B 2847/4885GRIN1 808/4885 |
| US-11655222-B2 | Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors | DPP4, DPP7, DPEP1 | GRIN2D 3407/4885GRIN3B 2847/4885GRIN1 808/4885 |
| US-20220016099-A1 | BENZIMIDAZOLE OR BENZOXAZOLE DERIVATIVES FOR PREVENTING AND TREATING CENTRAL NERVOUS SYSTEM DISEASE, DIABETES, AND COMPLICATIONS THEREOF | KEAP1, SLC5A1, GCLC | GRIN2D 761/4885GRIN3B 532/4885GRIN1 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.