Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983235 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| Cyclopentane SCHEMBL8879018 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| Cyclohexane SCHEMBL8879285 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| SCHEMBL11657362 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| SCHEMBL4989703 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| SCHEMBL822982 | 0.84 | — | — | |
| SCHEMBL112763 | 0.84 | KMT2A (0.52) | ALDH1A1KMT2AMCL1CA1CA2 | |
| Methane SCHEMBL27674323 | 0.82 | KMT2A (0.50) | ALDH1A1KMT2AMCL1CA1CA2 | |
| SCHEMBL822956 | 0.82 | — | — | |
| Methane SCHEMBL8878704 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9987217-B2 | Blackberry extract | SYMRISE AG (DE) | 2018-06-05 | — | — | US | disclosed |
| US-9706791-B2 | Aroma particles | SYMRISE AG (DE) | 2017-07-18 | — | — | US | disclosed |
| US-20140127390-A1 | AROMA PARTICLES | SYMRISE AG (DE) | 2014-05-08 | — | — | US | disclosed |
| US-8641945-B2 | Method of preparing aroma particles | SYMRISE AG (DE) | 2014-02-04 | — | — | US | disclosed |
| US-20100007040-A1 | Method of preparing aroma particles | SYMRISE GMBH & CO. KG (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-1761271-B1 | BLACKBERRY EXTRACT | SYMRISE GMBH & CO KG (DE) | 2008-12-03 | — | — | EP | disclosed |
| US-20080279791-A1 | Use of Isoeugenol Methyl Ester as an Agent Against Bad Breath | SYMRISE GMBH & CO. KG (DE) | 2008-11-13 | — | — | US | disclosed |
| EP-1919284-A1 | USE OF ISOEUGENOL METHYL ETHER AS AN AGENT AGAINST BAD BREATH | Symrise GmbH & Co. KG (DE) | 2008-05-14 | — | — | EP | disclosed |
| US-20080095719-A1 | Blackberry Extract | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | US | disclosed |
| US-20080063610-A1 | Use of Beta-Homocyclocitral as an Agent Against Bad Breath | SYMRISE GMBH & CO. KG (DE) | 2008-03-13 | — | — | US | disclosed |
| EP-1793795-A1 | USE OF BETA-HOMOCYCLOCITRAL AS AN AGENT AGAINST BAD BREATH | Symrise GmbH & Co. KG (DE) | 2007-06-13 | — | — | EP | disclosed |
| EP-1761271-A1 | BLACKBERRY EXTRACT | Symrise GmbH & Co. KG (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006032664-A1 | USE OF ISOEUGENOL METHYL ETHER AS AN AGENT AGAINST BAD BREATH | SYMRISE GMBH & CO. KG (DE) | 2006-03-30 | — | — | WO | disclosed |
| WO-2006032667-A1 | USE OF BETA-HOMOCYCLOCITRAL AS AN AGENT AGAINST BAD BREATH | SYMRISE GMBH & CO. KG (DE) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005123101-A1 | BLACKBERRY EXTRACT | SYMRISE GMBH & CO. KG (DE) | 2005-12-29 | — | — | WO | disclosed |
| US-20050220981-A1 | Aroma particles | SYMRISE AG (DE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063610-A1 | Use of Beta-Homocyclocitral as an Agent Against Bad Breath | BAD, BAX, BAK1 | ALDH1A1 3908/4885KDM4E 4519/4885LMNA 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.