Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529121 | 0.84 | CYP2A6 (0.47) | CYP2A6CYP2A13ALDH1A1ALDH1A3SMN1; SMN2 | |
| SCHEMBL27694001 | 0.81 | CYP2A6 (0.52) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL29084291 | 0.80 | ALDH1A3 (0.41) | CYP2A6CYP2A13ALDH1A1ALDH1A3SMN1; SMN2 | |
| SCHEMBL7995434 | 0.79 | ALDH1A3 (0.65) | CYP2A6CYP2A13ALDH1A1ALDH1A3SMN1; SMN2 | |
| SCHEMBL30893368 | 0.78 | ALDH1A3 (0.49) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL5685311 | 0.78 | ALDH1A3 (0.49) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL31299760 | 0.78 | CYP2A6 (0.48) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL6814384 | 0.78 | CYP2A6 (0.48) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL1874194 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ALDH1A3SMN1; SMN2ALDH3A1TSHR | |
| SCHEMBL8403813 | 0.76 | APP (0.62) | CYP2A6CYP2A13ALDH1A1ALDH1A3ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-02-02 | — | — | US | disclosed |
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-07-11 | — | — | US | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |
| CN-101605763-B | Radioprotector compounds and methods involving | PETER MACCALLUM CANCER INSTITUTE (AU) | 2016-03-09 | — | — | CN | disclosed |
| EP-2114896-B1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INST (AU) | 2015-07-22 | — | — | EP | disclosed |
| US-9023998-B2 | Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing | CARNEGIE MELLON UNIVERSITY (US) | 2015-05-05 | — | — | US | disclosed |
| US-9023998-B2 | Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing | CARNEGIE MELLON UNIVERSITY (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | CARNEGIE MELLON UNIVERSITY | 2014-08-28 | — | — | US | disclosed |
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | CARNEGIE MELLON UNIVERSITY | 2014-08-28 | — | — | US | disclosed |
| US-8796277-B2 | Radioprotector compounds and related methods | PETER MACCALLUM CANCER INSTITUTE (AU) | 2014-08-05 | — | — | US | disclosed |
| US-20100022557-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INSTITUTE (AU) | 2010-01-28 | — | — | US | disclosed |
| CN-100577663-C | Fused heterocyclic kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-01-06 | — | — | CN | disclosed |
| CN-101605763-A | Radioprotector compounds and methods involving | PETER MACCALLUM CANCER INST (AU) | 2009-12-16 | — | — | CN | disclosed |
| EP-2114896-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | Peter MacCallum Cancer Institute (AU) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008074091-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | PETER MACCALLUM CANCER INSTITUTE (AU) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243509-A1 | NEAR INFRARED FLUOROGEN AND FLUORESCENT ACTIVATING PROTEINS FOR IN VIVO IMAGING AND LIVE-CELL BIOSENSING | FUCA1, TYR, HBG2 | CYP2A6 1025/4885CYP2A13 893/4885ALDH1A1 1815/4885 |
| US-20100022557-A1 | RADIOPROTECTOR COMPOUNDS AND RELATED METHODS | RAD50, ERCC2, XRCC6 | CYP2A6 2292/4885CYP2A13 3527/4885ALDH1A1 905/4885 |
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | PSEN2, CLN6, MAPT | CYP2A6 4167/4885CYP2A13 4292/4885ALDH1A1 1121/4885 |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | PSEN2, SNCA, MAPT | CYP2A6 4399/4885CYP2A13 4479/4885ALDH1A1 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.