L-Citrulline

L-Citrulline

SCHEMBL3186407

Cc1cc(=O)oc2cc(N)ccc12.NC(=O)NCCC[C@H](N)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.55
KDM4E B2RXH2 9/20 0.55
HPGD P15428 9/20 0.55
HSD17B10 Q99714 7/20 0.55
CA12 O43570 4/20 0.55
CA9 Q16790 4/20 0.55
GLA P06280 3/20 0.55
GAA P10253 3/20 0.55
CA1 P00915 3/20 0.55
CASP1 P29466 2/20 0.55
CASP7 P55210 2/20 0.55
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH2 P05091 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
AKR1B1 P15121 1/20 0.41
UGT1A1 P22309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Citrulline SCHEMBL27758717 1.00 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDHSD17B10CA12
L-Citrulline SCHEMBL4192769 0.99 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDHSD17B10CA12
L-Citrulline SCHEMBL1824242 0.99 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDHSD17B10CA12
Arginine SCHEMBL27896326 0.92 ALDH1A1 (0.53) ALDH1A1KDM4EHPGDHSD17B10CA12
Arginine SCHEMBL29103422 0.91 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDHSD17B10CA12
Arginine SCHEMBL29131390 0.91 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDHSD17B10CA12
Arginine SCHEMBL29265137 0.89 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDHSD17B10CA12
Ornithine SCHEMBL6427980 0.86 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDHSD17B10CA12
Ornithine SCHEMBL4189046 0.85 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDHSD17B10CA12
Lysine SCHEMBL6425927 0.85 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDHSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1352083-B1 COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE BIOCONTROL SYSTEMS INC (US) 2005-10-26 EP claimed
EP-3589743-B1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER CO (US) 2023-06-21 EP disclosed
US-10301632-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2019-05-28 US disclosed
US-10301631-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2019-05-28 US disclosed
US-20180273957-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2018-09-27 US disclosed
US-20180273958-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2018-09-27 US disclosed
WO-2018160449-A1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER COMPANY (US) 2018-09-07 WO disclosed
US-20180245122-A1 RECOVERY MEDIUM FOR DETECTION OF MICROORGANISMS BY FLUORESCENCE AMERICAN STERILIZER COMPANY 2018-08-30 US disclosed
EP-2970992-B1 STERILIZATION INDICATOR INCLUDING A SIMPLIFIED GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2018-07-25 EP disclosed
US-10017772-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2018-07-10 US disclosed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US disclosed
US-8372624-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-02-12 US disclosed
US-20120214154-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2012-08-23 US disclosed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US disclosed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP disclosed
EP-0870054-B1 METHOD AND COMPOSITION FOR DETECTING BACTERIAL CONTAMINATION IN FOOD PRODUCTS BIOCONTROL SYSTEMS INC (US) 2008-07-30 EP disclosed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO disclosed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US disclosed
US-6472167-B1 MEASURE VIABLE BACTERIA AS A FUNCTION OF THE ACTIVITIES OF BACTERIAL ENZYMES, PHOSPHATASES, GLUCOSIDASES, AND AMINOPEPTIDASES; PRESENCE DETECTED BY A FLUORESCENT SIGNAL BIOCONTROL SYSTEMS, INC. 2002-10-29 US disclosed
US-6387650-B1 INNOCULATING AND INCUBATING TEST SAMPLE ON GROWTH MEDIUM HAVING ENZYME SUBSTRATES FOR PHOSPHATASE, GLYCOSIDASE, AND PEPTIDASE, THEN DETECTING OR MEASURING SIGNAL PRODUCED BY THE HYDROLYSIS OF THE SUBSTRATES BIOCONTROL SYSTEMS, INC. 2002-05-14 US disclosed