Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | GLA | P06280 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | CA9 | Q16790 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL4187796 | 0.98 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDGLAGAA | |
| Ornithine SCHEMBL6427980 | 0.97 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDGLAGAA | |
| Ornithine SCHEMBL4189046 | 0.96 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDGLAGAA | |
| Lysine SCHEMBL29009418 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGLAGAA | |
| D-Glutamate SCHEMBL28805166 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDGLAGAA | |
| Lysine SCHEMBL11213514 | 0.86 | GSR (0.47) | ALDH1A1KDM4EHPGDGLAGAA | |
| Glutamine SCHEMBL6427499 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDGLAGAA | |
| L-Citrulline SCHEMBL3186407 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGLAGAA | |
| Serine SCHEMBL6428011 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDGLAGAA | |
| Phenylalanine SCHEMBL7214651 | 0.84 | IGLV6-57 (0.43) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352083-B1 | COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE | BIOCONTROL SYSTEMS INC (US) | 2005-10-26 | — | — | EP | claimed |
| EP-0946746-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INC. (US) | 1999-10-06 | — | — | EP | claimed |
| WO-1998027223-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INCORPORATED (US) | 1998-06-25 | — | — | WO | claimed |
| EP-0946746-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027223-A1 | METHOD AND COMPONENTS FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | IDEXX LABORATORIES, INCORPORATED (US) | 1998-06-25 | — | — | WO | disclosed |