Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888238 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL15888179 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL22621227 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL14793682 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL10706157 | 0.81 | L3MBTL1 (0.57) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL27575333 | 0.79 | MEP1B (0.56) | SMN1; SMN2TP53TSHR | |
| SCHEMBL9770912 | 0.79 | CYP4F2 (0.57) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL15344564 | 0.79 | CYP4F2 (0.61) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL111861 | 0.78 | L3MBTL1 (0.64) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 | |
| SCHEMBL27537771 | 0.78 | TSHR (0.54) | SMN1; SMN2CYP1A2CYP2C19HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |