SCHEMBL3187010

SCHEMBL3187010

c1ccc(-c2nc3cc4sc(-c5ccccc5)nc4cc3s2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.68
SMN1; SMN2 Q16637 6/20 0.68
MAPT P10636 6/20 0.68
GAA P10253 5/20 0.68
ALDH1A1 P00352 5/20 0.68
HPGD P15428 4/20 0.68
GLA P06280 4/20 0.68
PKM P14618 4/20 0.68
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
NFKB1 P19838 7/20 0.64
NFKB2 Q00653 7/20 0.64
RELA Q04206 7/20 0.64
LMNA P02545 3/20 0.64
RAB9A P51151 10/20 0.55
NPC1 O15118 9/20 0.55
STAT1 P42224 1/20 0.55
APP P05067 3/20 0.53
POLB P06746 3/20 0.52
GFER P55789 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17404415 0.94 KDM4E (0.66) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL26746755 0.92 KDM4E (0.64) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL21166675 0.91 KDM4E (0.58) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL26745122 0.90 KDM4E (0.62) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL24466846 0.90 KDM4E (0.62) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL14193958 0.89 SMN1; SMN2 (0.58) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL23954319 0.89 APP (0.58) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL10424579 0.89 MAPT (0.62) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL26744930 0.88 KDM4E (0.60) KDM4ESMN1; SMN2MAPTGAAALDH1A1
SCHEMBL10423497 0.87 RAB9A (0.61) KDM4ESMN1; SMN2MAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
US-20230296820-A1 POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
US-20230296820-A1 POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20230228928-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230228928-A1 OPTICAL LAMINATE, POLARIZING PLATE, AND IMAGE DEVICE DISPLAY FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230183574-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CURED LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-06-15 US disclosed
US-20230143665-A1 FLUORINE-CONTAINING POLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230143665-A1 FLUORINE-CONTAINING POLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230135489-A1 FLUORINE-CONTAINING COPOLYMER, COMPOSITION, OPTICAL FILM, LIQUID CRYSTAL FILM, HARDCOAT FILM, AND POLARIZING PLATE FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20160170301-A1 METAL CATALYTIC COMPOSITION WITH SILVER N-HETEROCYCLC COMPLEX BANK OF AMERICA, N.A., AS AGENT 2016-06-16 US disclosed
US-20160167037-A1 FORMING CATALYTIC SITES FROM REDUCIBLE SILVER-HETEROCYCLIC COMPLEXES BANK OF AMERICA, N.A., AS AGENT 2016-06-16 US disclosed
US-20160167037-A1 FORMING CATALYTIC SITES FROM REDUCIBLE SILVER-HETEROCYCLIC COMPLEXES BANK OF AMERICA, N.A., AS AGENT 2016-06-16 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE KYULUX, INC. (JP) 2016-01-07 US disclosed
US-7670512-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-7671141-B2 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2010-03-02 US disclosed
US-20070004873-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-20070001154-A1 Second order nonlinear optical polyimides having benzobisthiazole-based pendant groups, and preparation of the same NATIONAL SUN YAT-SEN UNIVERSITY 2007-01-04 US disclosed
US-5558904-A Electroluminescent devices containing a conjugated polymer obtained via halogen precursor route chemistry XEROX CORPORATION (US) 1996-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160005978-A1 COMPOUND, LIGHT EMITTER, AND ORGANIC LIGHT EMITTING DEVICE DDT, DRD1, DRD2 KDM4E 3790/4885SMN1; SMN2 4840/4885MAPT 635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.