Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198496 | 0.96 | FAAH (0.50) | FAAHALDH1A1NAAAATMDGKA | |
| Potassium Ion SCHEMBL3196365 | 0.96 | FAAH (0.50) | FAAHALDH1A1NAAAATMDGKA | |
| SCHEMBL3200908 | 0.96 | FAAH (0.50) | FAAHALDH1A1NAAAATMDGKA | |
| SCHEMBL3191245 | 0.96 | FAAH (0.50) | FAAHALDH1A1NAAAATMDGKA | |
| Lithium Ion SCHEMBL3187444 | 0.94 | NAAA (0.59) | FAAHNAAADGKATSHRRAD52 | |
| Lithium Ion SCHEMBL3191064 | 0.92 | NAAA (0.62) | FAAHNAAADGKATSHRRAD52 | |
| Lithium Ion SCHEMBL28315834 | 0.92 | NAAA (0.62) | FAAHNAAADGKATSHRRAD52 | |
| SCHEMBL3205459 | 0.90 | NAAA (0.59) | FAAHNAAADGKATSHRRAD52 | |
| SCHEMBL3192696 | 0.90 | NAAA (0.59) | FAAHNAAADGKATSHRRAD52 | |
| Potassium Ion SCHEMBL3182251 | 0.90 | NAAA (0.59) | FAAHNAAADGKATSHRRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674330-B2 | Ink and ink-jet recording apparatus | CANON KABUSHIKI KAISHA (JP) | 2010-03-09 | — | — | US | disclosed |
| US-20080282930-A1 | INK AND INK-JET RECORDING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-11-20 | — | — | US | disclosed |