Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751606 | 0.76 | PGR (0.44) | ARMRGPRX4PGRTRPV4 | |
| SCHEMBL4200960 | 0.75 | SLC6A2 (0.49) | AR | |
| SCHEMBL177449 | 0.75 | AR (0.53) | ARMRGPRX4PGRTRPV4 | |
| SCHEMBL225912 | 0.74 | MRGPRX4 (0.48) | ARMRGPRX4TRPV4 | |
| SCHEMBL3916499 | 0.74 | MRGPRX4 (0.43) | ARMRGPRX4PGRTRPV4 | |
| SCHEMBL26127201 | 0.71 | AR (0.49) | ARMRGPRX4PGRTRPV4 | |
| SCHEMBL964004 | 0.71 | SLC6A2 (0.43) | ARPGR | |
| SCHEMBL964001 | 0.71 | SLC6A2 (0.43) | ARPGR | |
| SCHEMBL963999 | 0.71 | SLC6A2 (0.43) | ARPGR | |
| SCHEMBL964002 | 0.71 | SLC6A2 (0.43) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590930-B1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI SA (FR) | 2015-02-25 | — | — | EP | disclosed |
| EP-2590930-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |