Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 11/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748849 | 0.84 | AR (0.43) | ARMRGPRX4ESRRA | |
| SCHEMBL177449 | 0.78 | AR (0.53) | PGRARMRGPRX4NR3C1TRPV4 | |
| SCHEMBL318774 | 0.76 | AR (0.42) | PGRARMRGPRX4TRPV4 | |
| SCHEMBL4200960 | 0.75 | SLC6A2 (0.49) | AR | |
| SCHEMBL473954 | 0.73 | AR (0.49) | PGRARMRGPRX4NR3C1TRPV4 | |
| SCHEMBL26127201 | 0.71 | AR (0.49) | PGRARMRGPRX4NR3C1TRPV4 | |
| SCHEMBL10777839 | 0.71 | AR (0.49) | PGRARMRGPRX4TRPV4ESRRA | |
| SCHEMBL3177878 | 0.68 | PGR (0.62) | PGRARTRPV4 | |
| SCHEMBL27376804 | 0.68 | AR (0.52) | PGRARMRGPRX4NR3C1TRPV4 | |
| SCHEMBL3188688 | 0.68 | PGR (0.62) | PGRARTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |