Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CEL | P19835 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 2/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177384 | 0.85 | CEL (0.37) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL3190595 | 0.78 | CEL (0.40) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL31240954 | 0.71 | HTR2C (0.52) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL3170231 | 0.70 | CEL (0.35) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL42781 | 0.70 | PTGDR2 (0.48) | PTGS2CELPTGDR2HTR2CADRA2A | |
| SCHEMBL239469 | 0.69 | ABCB1 (0.43) | HTR1AHTR7PTGS2CELPTGDR2 | |
| Benzene SCHEMBL27853973 | 0.68 | PTGDR2 (0.52) | PTGS2CELPTGDR2HTR2CKMO | |
| SCHEMBL779938 | 0.67 | CHRNB4 (0.46) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL201424 | 0.67 | CEL (0.46) | HTR1AHTR7PTGS2CELPTGDR2 | |
| SCHEMBL3183482 | 0.67 | CEL (0.46) | HTR1AHTR7PTGS2CELPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133357-B1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO LTD (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-8076430-B2 | Living radical polymerization promoter | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2133357-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | Otsuka Chemical Holdings Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | DNMT1, CYP1B1, DNMT3B | HTR1A 2983/4885HTR7 2104/4885PTGS2 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.