Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188236 | 0.85 | HTR1A (0.36) | CELPDCD1CD274PTGDR2PTGS2 | |
| SCHEMBL3190595 | 0.81 | CEL (0.40) | CELPDCD1CD274PTGDR2PTGS2 | |
| SCHEMBL3170231 | 0.73 | CEL (0.35) | CELPDCD1CD274PTGDR2PTGS2 | |
| SCHEMBL42781 | 0.73 | PTGDR2 (0.48) | CELPTGDR2PTGS2CYP11B2TDO2 | |
| SCHEMBL239469 | 0.72 | ABCB1 (0.43) | CELPDCD1CD274PTGDR2PTGS2 | |
| Benzene SCHEMBL27853973 | 0.71 | PTGDR2 (0.52) | CELPTGDR2PTGS2KMOCYP11B2 | |
| SCHEMBL779938 | 0.70 | CHRNB4 (0.46) | CELPTGDR2PTGS2HTR1AHTR7 | |
| SCHEMBL1483812 | 0.70 | CEL (0.41) | CELPDCD1CD274PTGDR2PTGS2 | |
| SCHEMBL3183482 | 0.70 | CEL (0.46) | CELPDCD1CD274PTGDR2PTGS2 | |
| SCHEMBL4960398 | 0.70 | PTPN5 (0.46) | CELPTGDR2PTGS2HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076430-B2 | Living radical polymerization promoter | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2133357-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | Otsuka Chemical Holdings Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | DNMT1, CYP1B1, DNMT3B | CEL 2032/4885PDCD1 4823/4885CD274 4734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.