SCHEMBL3188409

SCHEMBL3188409

C=CC(=O)OCCN(F)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.38
ALDH1A1 P00352 4/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.35
THRB P10828 2/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
MMP1 P03956 3/20 0.31
MMP2 P08253 3/20 0.31
MMP9 P14780 3/20 0.31
MMP8 P22894 3/20 0.31
MMP13 P45452 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399535 0.99 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11787519 0.90 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30424942 0.86 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL301354 0.85 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16178607 0.84 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17891351 0.84 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1930958 0.84 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31127935 0.84 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7906773 0.83 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7920244 0.82 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6894105-B2 Dyed fluoropolymers 3M INNOVATIVES PROPERTIES COMPANY (US) 2005-05-17 US claimed
EP-1525240-A1 DYED FLUOROPOLYMERS 3M Innovative Properties Company (US) 2005-04-27 EP claimed
WO-2004011512-A1 DYED FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO claimed
US-20040024100-A1 Dyed fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US claimed
US-7682771-B2 fluorochemical acrylic copolymers bearing pendant groups comprising benzophenone, substituted benzophenone, acetophenone, or substituted acetophenone moieties which can generate free radicals upon irradiation with ultraviolet light sources 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-03-23 US disclosed
EP-1697579-B1 FLUOROCHEMICAL OLIGOMERIC COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2009-08-19 EP disclosed
EP-1833862-B1 COMPOSITIONS CONTAINING PHOTOSENSITIVE FLUOROCHEMICAL AND USES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2009-02-18 EP disclosed
US-7300976-B2 Fluorochemical oligomeric polish composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-27 US disclosed
EP-1833862-A1 COMPOSITIONS CONTAINING PHOTOSENSITIVE FLUOROCHEMICAL AND USES THEREOF 3M Innovative Properties Company (US) 2007-09-19 EP disclosed
US-7253241-B2 Fluorochemical containing low adhesion backsize 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-08-07 US disclosed
EP-1781747-A1 FLUOROCHEMICAL OLIGOMERIC POLISH COMPOSITION 3M Innovative Properties Company (US) 2007-05-09 EP disclosed
US-20060199029-A1 Compositions containing photosensitive fluorochemical and uses thereof 3M INNOVATIVE PROPERTIES COMPANY 2006-09-07 US disclosed
US-20050113508-A1 Using a fluorochemical oligomeric component which is a reaction product of a fluorochemical oligomer and an isocyanate of the formula R1(NCO)x, wherein x is 1 to 6, wherein R1 is an aliphatic, alicyclic or aromatic group, and an antisoilant for treating fibrous substrate 3M INNOVATIVE PROPERTIES COMPANY 2005-05-26 US disclosed
US-6894105-B2 Dyed fluoropolymers 3M INNOVATIVES PROPERTIES COMPANY (US) 2005-05-17 US disclosed
EP-1525240-A1 DYED FLUOROPOLYMERS 3M Innovative Properties Company (US) 2005-04-27 EP disclosed
EP-1525268-A1 FUNCTIONAL FLUORESCENT DYES 3M Innovative Properties Company (US) 2005-04-27 EP disclosed
WO-2004011557-A1 FUNCTIONAL FLUORESCENT DYES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO disclosed
WO-2004011512-A1 DYED FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO disclosed
US-20040024100-A1 Dyed fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed
US-20040016370-A1 Functional fluorescent dyes 3M INNOVATIVE PROPERTIES COMPANY 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040016370-A1 Functional fluorescent dyes ARL1, HACL2, GLB1 TSHR 2861/4885ALDH1A1 316/4885TP53 1794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.