SCHEMBL5399535

SCHEMBL5399535

C=CC(=O)OCCN(F)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.37
ALDH1A1 P00352 4/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
HPGD P15428 1/20 0.34
THRB P10828 2/20 0.33
CA2 P00918 4/20 0.32
CA1 P00915 3/20 0.32
MMP1 P03956 3/20 0.32
MMP2 P08253 3/20 0.32
MMP9 P14780 3/20 0.32
MMP8 P22894 3/20 0.32
MMP13 P45452 3/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3188409 0.99 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11787519 0.91 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30424942 0.88 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16178607 0.85 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31127935 0.85 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL17891351 0.85 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1930958 0.85 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL301354 0.84 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7920244 0.83 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7920243 0.83 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6168866-B1 TO IMPART PROPERTIES SUCH AS SOIL- AND ABRASION-RESISTANCE WHEN APPLIED TO SUBSTRATE MATERIALS 3M INNOVATIVE PROPERTIES COMPANY 2001-01-02 US claimed
US-3950298-A TEXTILE COATING, OLEOPHOBICITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-04-13 US claimed
WO-2020067374-A1 ORIGINAL PLATE FOR PRINTING, LAMINATE OF ORIGINAL PLATE FOR PRINTING, METHOD FOR MANUFACTURING PRINTING PLATE, AND PRINTING METHOD 富士フイルム株式会社 2020-04-02 WO disclosed
WO-2020067373-A1 ORIGINAL PLATE FOR PRINTING, LAMINATE OF ORIGINAL PLATE FOR PRINTING, METHOD FOR PLATEMAKING PRINTING PLATE, AND PRINTING METHOD 富士フイルム株式会社 2020-04-02 WO disclosed
US-7300976-B2 Fluorochemical oligomeric polish composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-11-27 US disclosed
EP-1230312-B1 POLISH COMPOSITION AND METHOD OF USE 3M INNOVATIVE PROPERTIES CO (US) 2006-12-13 EP disclosed
EP-1214297-B1 FLUOROCHEMICAL OLIGOMER AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2006-12-06 EP disclosed
US-7078456-B2 Fluorochemical oligomeric composition and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-18 US disclosed
US-7049379-B2 Alkylated fluorochemical oligomers and use thereof in the treatment of fibrous substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-05-23 US disclosed
US-20050277718-A1 Fluorochemical oligomeric polish composition 3M INNOVATIVE PROPERTIES COMPANY 2005-12-15 US disclosed
US-20050113508-A1 Using a fluorochemical oligomeric component which is a reaction product of a fluorochemical oligomer and an isocyanate of the formula R1(NCO)x, wherein x is 1 to 6, wherein R1 is an aliphatic, alicyclic or aromatic group, and an antisoilant for treating fibrous substrate 3M INNOVATIVE PROPERTIES COMPANY 2005-05-26 US disclosed
WO-1992015626-A1 GRAFT COPOLYMERS CONTAINING FLUOROALIPHATIC GROUPS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-17 WO disclosed
WO-1992015748-A1 COMPOSITION FOR PROVIDING OIL AND WATER REPELLENCY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-17 WO disclosed
US-5147938-A Reduced surface tension, aging resistance MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-09-15 US disclosed
EP-0084220-B1 CELLULAR PRESSURE-SENSITIVE ADHESIVE PRODUCT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-07 EP disclosed
EP-0084220-A1 Cellular pressure-sensitive adhesive product MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
US-3995085-A IMPARTING SOIL AND STAIN REPELLENCY PROPERTIES TO FABRICS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-11-30 US disclosed
US-3993833-A FLUOROALIPHATIC FOAM STABILIZER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-11-23 US disclosed
US-3950298-A TEXTILE COATING, OLEOPHOBICITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-04-13 US disclosed
US-3944527-A HYBRID MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-03-16 US disclosed