Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL3891720 | 0.95 | LOXL2 (0.74) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL2841170 | 0.92 | LOXL2 (0.78) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL2841167 | 0.92 | LOXL2 (0.78) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL6429492 | 0.90 | LOXL2 (0.74) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL8464909 | 0.90 | LOXL2 (0.74) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL25352130 | 0.90 | LOXL2 (0.74) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL9567530 | 0.90 | LOXL2 (0.74) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL27810067 | 0.89 | LOXL2 (0.58) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL27781209 | 0.89 | LOXL2 (0.93) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 | |
| Benzylamine SCHEMBL20593186 | 0.87 | LOXL2 (0.70) | LOXL2TSHRCYP2C19CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929340-A | Proline boric acid compound and its preparation method and application | 北京大学 | 2018-12-04 | — | — | CN | disclosed |
| CN-106588965-A | Urea peptidomimetic boric acid compound as well as pharmaceutical composition, preparation method and application thereof | 北京大学 | 2017-04-26 | — | — | CN | disclosed |
| US-7662960-B2 | Beta-strand mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2010-02-16 | — | — | US | disclosed |
| EP-1646633-B1 | BETA-STRAND MIMETICS | CHOONGWAE PHARMA CORP (KR) | 2009-04-15 | — | — | EP | disclosed |
| CN-1802378-A | Beta-strand mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-07-12 | — | — | CN | disclosed |
| EP-1646633-A1 | BETA-STRAND MIMETICS AND METHOD RELATING THERETO | Choongwae Pharma Corporation (KR) | 2006-04-19 | — | — | EP | disclosed |
| WO-2004108731-A1 | BETA-STRAND MIMETICS AND METHOD RELATING THERETO | CHOONGWAE PHARMA CORPORATION (KR) | 2004-12-16 | — | — | WO | disclosed |
| US-20040053331-A1 | Beta-strand mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053331-A1 | Beta-strand mimetics and method relating thereto | BIRC5, BIRC7, XIAP | LOXL2 3477/4885TSHR 3687/4885CYP2C19 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.