Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL6429492 | 1.00 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL29167055 | 0.97 | LOXL2 (0.70) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL2841167 | 0.92 | LOXL2 (0.78) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL2841170 | 0.92 | LOXL2 (0.78) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL25352130 | 0.90 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL9567530 | 0.90 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL3891720 | 0.90 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL3188490 | 0.90 | LOXL2 (0.74) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL27781209 | 0.89 | LOXL2 (0.93) | LOXL2CYP1A2CYP2D6CYP2C9TSHR | |
| Benzylamine SCHEMBL1256239 | 0.87 | LOXL2 (0.70) | LOXL2CYP1A2CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5911099-A | Electroconductiive member and electrophotogrpahic apparatus | BRIDGESTONE CORPORATION (JP) | 1999-06-08 | — | — | US | disclosed |