Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266656 | 0.75 | ALDH1A1 (0.75) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| SCHEMBL3188806 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| SCHEMBL7450723 | 0.74 | TDP1 (0.47) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| SCHEMBL10495669 | 0.72 | POLB (0.54) | ALDH1A1SENP7MEN1KMT2AMAPK1 | |
| SCHEMBL7538896 | 0.72 | ALDH1A1 (0.40) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| SCHEMBL11852806 | 0.69 | THRB (0.46) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| SCHEMBL11852801 | 0.69 | THRB (0.46) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| Azobenzene SCHEMBL6562161 | 0.69 | ALDH1A1 (1.00) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| Azobenzene SCHEMBL6703357 | 0.69 | ALDH1A1 (1.00) | ALDH1A1CASP3SENP7SENP6SENP8 | |
| Azobenzene SCHEMBL11878769 | 0.69 | ALDH1A1 (1.00) | ALDH1A1CASP3SENP7SENP6SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659325-B2 | Functionalized dyes and use thereof in ophthalmic lens material | OPHTEC B.V. (NL) | 2010-02-09 | — | — | US | disclosed |
| EP-1783518-B1 | Functionalized dyes and use thereof in ophthalmic lens material | OPHTEC BV (NL) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007053012-A1 | FUNCTIONALIZED DYES AND USE THEREOF IN OPHTHALMIC LENS MATERIAL | OPHTEC B.V. (NL) | 2007-05-10 | — | — | WO | disclosed |
| EP-1783518-A1 | Functionalized dyes and use thereof in ophthalmic lens material | Ophtec B.V. (NL) | 2007-05-09 | — | — | EP | disclosed |
| US-20070100018-A1 | Functionalized dyes and use thereof in ophthalmic lens material | OPHTEC B.V. (NL) | 2007-05-03 | — | — | US | disclosed |