Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196911 | 0.96 | MMP1 (0.40) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3197766 | 0.94 | MMP1 (0.41) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3187992 | 0.91 | MMP1 (0.41) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3186390 | 0.89 | CYP3A4 (0.40) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3178915 | 0.88 | MMP1 (0.49) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3195314 | 0.84 | CYP3A4 (0.43) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3199556 | 0.83 | MMP2 (0.43) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3197621 | 0.81 | MMP1 (0.45) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL3177510 | 0.81 | KAT6A (0.37) | ALDH1A1MEN1KMT2AATM | |
| SCHEMBL3189816 | 0.80 | CYP3A4 (0.44) | MMP1MMP2MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671075-B2 | Substituted phenylsulfonamide inhibitors of beta amyloid production | WYETH (US) | 2010-03-02 | — | — | US | claimed |