SCHEMBL3189196

SCHEMBL3189196

COc1c(OCC(=O)OC(C)(C)C)cccc1[S+](c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 3/20 0.39
MAPT P10636 2/20 0.39
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
PTPN1 P18031 1/20 0.35
ACLY P53396 1/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 2/20 0.35
GLA P06280 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3181612 0.93 HPGD (0.40) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3190242 0.91 HPGD (0.39) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3193906 0.91 GAA (0.40) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL30440133 0.87 POLB (0.43) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3183450 0.86 MAPT (0.37) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3194016 0.85 DDB1 (0.47) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3190355 0.85 ACLY (0.40) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3193143 0.83 KMT2A (0.41) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3190419 0.83 POLB (0.44) POLBSMN1; SMN2NPSR1MAPTDDB1
SCHEMBL3182266 0.83 MAPT (0.40) POLBNPSR1MAPTDDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed
US-20020090569-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-07-11 US disclosed