Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189493 | 1.00 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3194087 | 0.89 | EPHX2 (0.66) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3194077 | 0.89 | EPHX2 (0.66) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3182153 | 0.89 | EPHX2 (0.74) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3182145 | 0.89 | EPHX2 (0.74) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3178477 | 0.88 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3178470 | 0.88 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3181050 | 0.87 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3181043 | 0.87 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3172705 | 0.87 | EPHX2 (0.72) | EPHX2MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |