Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194087 | 1.00 | EPHX2 (0.66) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3190084 | 0.91 | EPHX2 (0.68) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3190094 | 0.91 | EPHX2 (0.68) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3178470 | 0.90 | EPHX2 (0.72) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3178477 | 0.90 | EPHX2 (0.72) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3189493 | 0.89 | EPHX2 (0.72) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3189486 | 0.89 | EPHX2 (0.72) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3189587 | 0.89 | EPHX2 (0.66) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3189594 | 0.89 | EPHX2 (0.66) | EPHX2ALDH1A1KDM4ENPC1EPHX1 | |
| SCHEMBL3192516 | 0.89 | EPHX2 (0.66) | EPHX2ALDH1A1KDM4ENPC1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |