Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA1 | P00915 | 8/20 | 1.00 |
| ▸ | CA7 | P43166 | 8/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | CASP1 | P29466 | 3/20 | 0.64 |
| ▸ | CASP7 | P55210 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217910 | 0.87 | CA9 (0.77) | CA9CA12CA1CA7CA13 | |
| SCHEMBL30098746 | 0.85 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3924718 | 0.85 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3190311 | 0.85 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL29396102 | 0.85 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| Methoxymethane SCHEMBL2253445 | 0.84 | CA9 (0.97) | CA9CA12CA1CA7CA13 | |
| SCHEMBL30819206 | 0.83 | CA12 (0.73) | CA9CA12CA1CA7CA13 | |
| SCHEMBL28324995 | 0.83 | CA12 (0.73) | CA9CA12CA1CA7CA13 | |
| SCHEMBL7519444 | 0.82 | CA9 (0.68) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3362753 | 0.82 | CA9 (0.70) | CA9CA12CA1CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006118553-A1 | COMPOSITIONS COMPRISING NATURAL AGENTS FOR THE TREATMENT OF HIV-ASSOCIATED OPPORTUNISTIC INFECTIONS AND COMPLICATIONS AND METHODS FOR PREPARING AND USING COMPOSITIONS COMPRISING NATURAL AGENTS | WUTOH ANTHONY K (US) | 2006-11-09 | — | — | WO | claimed |
| US-20050266105-A1 | Compositions comprising natural agents for the treatment of HIV-associated opportunistic infections and complications and methods for preparing and using compositions comprising natural agents | ASHIAGBOR KWAME T | 2005-12-01 | — | — | US | claimed |
| CN-112930344-B | bioactive compounds | 哈迪健康有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-113841557-A | Method for increasing content of coumarins in chimonanthus salicifolius | 丽水市农林科学研究院 | 2021-12-28 | — | — | CN | disclosed |
| US-9150608-B2 | Neuro-protective compounds and their use | Biotechnology Research Corp. Ltd. (CN) | 2015-10-06 | — | — | US | disclosed |
| US-9150608-B2 | Neuro-protective compounds and their use | Biotechnology Research Corp. Ltd. (CN) | 2015-10-06 | — | — | US | disclosed |
| US-8772252-B2 | Coumarin compounds as melanogenesis modifiers and uses thereof | NEW YORK UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-8772252-B2 | Coumarin compounds as melanogenesis modifiers and uses thereof | NEW YORK UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| CN-103599145-A | Helleborus thibetanus extract, separation method of effective components in Helleborus thibetanus extract and compounds obtained by separation method | GUIYANG COLLEGE TRADITIONAL CHINESE MEDICINE | 2014-02-26 | — | — | CN | disclosed |
| US-8563754-B2 | Compounds, compositions and methods for preventing skin darkening | NEW YORK UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| US-8563754-B2 | Compounds, compositions and methods for preventing skin darkening | NEW YORK UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| CN-102946877-A | Neuroprotective effect of mastoid fruits (Adelostemma gracilimum) and isolated compounds thereof | BIOTECHNOLOGY RES CORP LTD | 2013-02-27 | — | — | CN | disclosed |
| US-20120220545-A1 | COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF | NEW YORK UNIVERSITY | 2012-08-30 | — | — | US | disclosed |
| US-20120220545-A1 | COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF | NEW YORK UNIVERSITY | 2012-08-30 | — | — | US | disclosed |
| CN-101735187-B | Method for extracting coumarin compound from willow leaf calyx canthus | JIANG University OF TECHNOLOGY (CN) | 2012-02-22 | — | — | CN | disclosed |
| WO-2011114220-A1 | NEURO-PROTECTIVE EFFECTS OF ADELOSTEMMA GRACILLIMUM AND ITS ISOLATED COMPOUNDS | BIOTECHNOLOGY RESEARCH CORPORATION LIMITED (CN) | 2011-09-22 | — | — | WO | disclosed |
| US-20110190229-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING | NEW YORK UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
| US-20110190229-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING | NEW YORK UNIVERSITY | 2011-08-04 | — | — | US | disclosed |
| CN-101735187-A | Method for extracting coumarin compound from willow leaf calyx canthus | UNIV ZHEJIANG TECHNOLOGY | 2010-06-16 | — | — | CN | disclosed |
| EP-1763520-B1 | USE OF TRISUBSTITUTED BENZOPYRANONES | SCHWABE WILLMAR GMBH & CO (DE) | 2008-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050266105-A1 | Compositions comprising natural agents for the treatment of HIV-associated opportunistic infections and complications and methods for preparing and using compositions comprising natural agents | ZAP70, LSS, ITGAM | CA9 2493/4885CA12 2162/4885CA1 4711/4885 |
| US-20120220545-A1 | COUMARIN COMPOUNDS AS MELANOGENESIS MODIFIERS AND USES THEREOF | TYR, MC1R, MITF | CA9 3115/4885CA12 3697/4885CA1 4178/4885 |
| US-20110190229-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING SKIN DARKENING | TYR, MC1R, MITF | CA9 2461/4885CA12 3253/4885CA1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.