Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 9/20 | 0.77 |
| ▸ | CA12 | O43570 | 8/20 | 0.77 |
| ▸ | CA1 | P00915 | 7/20 | 0.77 |
| ▸ | CA7 | P43166 | 7/20 | 0.77 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | CASP1 | P29466 | 4/20 | 0.67 |
| ▸ | CASP7 | P55210 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819206 | 0.88 | CA12 (0.73) | CA9CA12CA1CA7CA13 | |
| SCHEMBL28324995 | 0.88 | CA12 (0.73) | CA9CA12CA1CA7CA13 | |
| SCHEMBL29396102 | 0.87 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3190311 | 0.87 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| Methoxymethane SCHEMBL2253445 | 0.86 | CA9 (0.97) | CA9CA12CA1CA7CA13 | |
| SCHEMBL5427865 | 0.81 | CA9 (0.64) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3924718 | 0.81 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| SCHEMBL30098746 | 0.81 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| SCHEMBL15171965 | 0.80 | CA12 (0.63) | CA9CA12CA1CA7CA13 | |
| Fraxetin SCHEMBL30010613 | 0.80 | CA9 (1.00) | CA9CA12CA1CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763520-B1 | USE OF TRISUBSTITUTED BENZOPYRANONES | SCHWABE WILLMAR GMBH & CO (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1763520-B1 | USE OF TRISUBSTITUTED BENZOPYRANONES | SCHWABE WILLMAR GMBH & CO (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-20080020068-A1 | Use Of Trisubstituted Benzopyranones | DR.WILLMAR SCHWABE GMBH & CO. KG (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080020068-A1 | Use Of Trisubstituted Benzopyranones | DR.WILLMAR SCHWABE GMBH & CO. KG (DE) | 2008-01-24 | — | — | US | disclosed |
| EP-1763520-A2 | USE OF TRISUBSTITUTED BENZOPYRANONES | Dr. Willmar Schwabe GmbH & Co. KG (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006002918-A2 | USE OF TRISUBSTITUTED BENZOPYRANONES | DR. WILLMAR SCHWABE GMBH & CO. KG (DE) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020068-A1 | Use Of Trisubstituted Benzopyranones | PTGS1, PTGES, NFKBIA | CA9 4658/4885CA12 3626/4885CA1 3195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.