SCHEMBL3190751

SCHEMBL3190751

CC(C)(C)Oc1cc(OC(C)(C)C)cc([S+](c2ccccc2)c2ccccc2)c1.O=S(=O)([O-])c1ccc(C(F)(F)F)cc1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR2 P30518 2/20 0.35
GPR27 Q9NS67 2/20 0.35
POLQ O75417 2/20 0.34
ABCB11 O95342 1/20 0.33
MCL1 Q07820 2/20 0.32
AR P10275 2/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
ESR2 Q92731 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
HSD11B1 P28845 1/20 0.32
SLC40A1 Q9NP59 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK10 P53779 1/20 0.32
ALPL P05186 1/20 0.31
FLT1 P17948 1/20 0.31
FLT4 P35916 1/20 0.31
KDR P35968 1/20 0.31
CNR2 P34972 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192962 0.89 POLQ (0.32) AVPR2GPR27POLQ
SCHEMBL3190556 0.89 AR (0.35) AVPR2GPR27ARNR3C1PGR
SCHEMBL3202130 0.88 MCL1 (0.34) AVPR2GPR27POLQABCB11MCL1
SCHEMBL3201793 0.88 ABCB11 (0.36) AVPR2GPR27POLQABCB11MCL1
SCHEMBL3194611 0.84 HSD11B1 (0.33) AVPR2GPR27ABCB11MCL1AR
SCHEMBL3189160 0.84 AVPR2 (0.37) AVPR2GPR27POLQABCB11MCL1
SCHEMBL3191633 0.83 ABCB11 (0.37) AVPR2GPR27ABCB11MCL1SLC22A12
SCHEMBL3202131 0.83 PSEN1 (0.46) AVPR2GPR27POLQ
SCHEMBL3183398 0.81
SCHEMBL3192045 0.80 SLC22A12 (0.39) SLC22A12HSD11B1MAPK8MAPK10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed