Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 6/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CRYAB | P02511 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191480 | 1.00 | MAPK1 (0.51) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL26642848 | 0.82 | MAPK1 (0.61) | MAPK1ACHETOP2ATOP2BUSP2 | |
| SCHEMBL26642849 | 0.82 | MAPK1 (0.61) | MAPK1ACHETOP2ATOP2BUSP2 | |
| SCHEMBL31097469 | 0.81 | MAPK1 (0.75) | MAPK1ACHEHMGCRTOP2AUSP2 | |
| SCHEMBL1196805 | 0.81 | MAPK1 (0.50) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL1196806 | 0.81 | MAPK1 (0.50) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL13384621 | 0.80 | HMGCR (0.58) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL19728965 | 0.78 | MAPK1 (0.48) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL31232805 | 0.77 | RELA (0.49) | MAPK1ACHEHMGCRTOP2ATOP2B | |
| SCHEMBL3303674 | 0.77 | TOP2A (0.63) | MAPK1ACHEHMGCRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100028469-A1 | Extracts of Cranberry and Methods of Using Thereof | HERBALSCIENCE GROUP, LLC (US) | 2010-02-04 | — | — | US | disclosed |