SCHEMBL3191963

SCHEMBL3191963

C=CC(=O)OC(CC)[SiH](C)OCC(C)C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444360 0.86 TSHR (0.49) TSHRHPGD
SCHEMBL28131009 0.80 TSHR (0.36) TSHRHPGD
SCHEMBL9546118 0.80 TSHR (0.36) TSHRHPGD
SCHEMBL5858565 0.78 TSHR (0.47) TSHR
SCHEMBL28025375 0.78 TSHR (0.39) TSHRHPGD
SCHEMBL29018512 0.76 TSHR (0.38) TSHRHPGD
SCHEMBL28027541 0.76 TSHR (0.33) TSHRHPGD
SCHEMBL29057324 0.75 TSHR (0.41) TSHRHPGD
SCHEMBL27986825 0.75 TGM2 (0.37) TSHR
SCHEMBL143214 0.73 TSHR (0.36) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7659345-B2 S,S′-bis-(α, α′-Disubstituted-α″-Acetic acid)—trithiocarbonates and derivatives as initiator—chain transfer agent—terminator for controlled radical polymerizations and the process for making the same LUBRIZOL ADVANCED MATERIALS, INC. (US) 2010-02-09 US disclosed
US-20090005529-A1 S-S'-bis-(Alpha, Alpha'-Disubstituted-Alpha\"-Acetic Acid) - Trithiocarbonates and Derivatives as Initiator - Chain Transfer Agent - Terminator for Controlled Radical Polymerizations and the Process for Making the Same LAI JOHN T 2009-01-01 US disclosed