Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17733685 | 0.91 | TDP1 (0.42) | TDP1L3MBTL1NAAAENPP2IDO1 | |
| SCHEMBL9479894 | 0.82 | PLA2G4B (0.47) | MRGPRX4TDP1L3MBTL1 | |
| SCHEMBL21968364 | 0.81 | IDO1 (0.53) | TDP1L3MBTL1CHRM3IDO1LMNA | |
| SCHEMBL661713 | 0.81 | CYP4F2 (0.44) | MRGPRX4ENPP2CYP4F2CYP4A11PRSS1 | |
| SCHEMBL6782118 | 0.81 | MRGPRX4 (0.44) | MRGPRX4ENPP2CYP4F2CYP4A11PRSS1 | |
| SCHEMBL23640522 | 0.80 | IDO1 (0.57) | TDP1L3MBTL1CHRM3IDO1AGXT | |
| SCHEMBL2567350 | 0.80 | MRGPRX4 (0.49) | MRGPRX4ENPP2CYP4F2CYP4A11PRSS1 | |
| SCHEMBL6667804 | 0.80 | MRGPRX4 (0.51) | MRGPRX4ENPP2CYP4F2CYP4A11PRSS1 | |
| SCHEMBL2811503 | 0.79 | CYP4F2 (0.46) | ENPP2CYP4F2CYP4A11CHRM3KDM4E | |
| SCHEMBL8263369 | 0.79 | DAO (0.40) | TDP1L3MBTL1GBA1UGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | MRGPRX4 456/4885TDP1 3607/4885L3MBTL1 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.