Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.78 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.69 |
| ▸ | MDM4 | O15151 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.69 |
| ▸ | VDR | P11473 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360882 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL18092664 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL1177397 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL18092678 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL11406748 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL1177394 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL18092622 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL11408265 | 0.90 | USP2 (0.75) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL26653550 | 0.89 | NPC1L1 (0.88) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL26653612 | 0.89 | USP2 (0.81) | LMNAUSP2NPC1L1GPBAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233960-A | Preparation method of 3-hydroxy-6-ketocholanic acid with low cost and high yield | 上海慈瑞医药科技股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| US-4486532-A | IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM | TNANBE SEIYAKU CO., LTD. (JP) | 1984-12-04 | — | — | US | claimed |
| CN-111233960-A | Preparation method of 3-hydroxy-6-ketocholanic acid with low cost and high yield | 上海慈瑞医药科技股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-111233960-A | Preparation method of 3-hydroxy-6-ketocholanic acid with low cost and high yield | 上海慈瑞医药科技股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |
| US-20100028469-A1 | Extracts of Cranberry and Methods of Using Thereof | HERBALSCIENCE GROUP, LLC (US) | 2010-02-04 | — | — | US | disclosed |
| US-4486532-A | IMMOBILIZATION OF FUMARASE-PRODUCING MICROORGANISM | TNANBE SEIYAKU CO., LTD. (JP) | 1984-12-04 | — | — | US | disclosed |
| US-4460509-A | STEROIDS WITH HETERO RING SIDE CHAIN | BETH ISRAEL MEDICAL CENTER (US) | 1984-07-17 | — | — | US | disclosed |