Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.78 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.69 |
| ▸ | MDM4 | O15151 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.69 |
| ▸ | VDR | P11473 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092664 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL1177397 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL18092678 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL3192872 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL11406748 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL1177394 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL18092622 | 1.00 | LMNA (0.78) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL11408265 | 0.90 | USP2 (0.75) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL26653550 | 0.89 | NPC1L1 (0.88) | LMNAUSP2NPC1L1GPBAR1MAPT | |
| SCHEMBL26653612 | 0.89 | USP2 (0.81) | LMNAUSP2NPC1L1GPBAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259837-A1 | Use of Non-Glucocorticoid Steroids for the Treatment of Muscular Dystrophy | UTRN, MTPN, NR3C1 | LMNA 348/4885USP2 3948/4885NPC1L1 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.