Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD17B14 | Q9BPX1 | 9/20 | 0.51 |
| ▸ | CTSA | P10619 | 5/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319710 | 0.88 | CTSA (0.56) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL13758107 | 0.81 | KDM4E (0.53) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL318982 | 0.81 | KDM4E (0.57) | KDM4EALOX15TSHRACMSDTDP1 | |
| 2-Picolinic Acid SCHEMBL5670387 | 0.79 | LMNA (0.56) | KDM4EHSD17B14CTSAKMO | |
| SCHEMBL1725525 | 0.79 | KDM4E (0.46) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29357675 | 0.78 | KDM4E (0.76) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL70765 | 0.78 | KDM4E (0.76) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL28554483 | 0.78 | CTSA (0.53) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL11907284 | 0.78 | KMO (0.60) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL16898859 | 0.78 | NAPRT (0.49) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112794860-B | Oxazole pyrimidone amide compound or medicinal salt thereof, preparation method and application | 上海肇钰医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-112794860-A | Oxazole pyrimidone amide compound or medicinal salt thereof, preparation method and application | 上海肇钰医药科技有限公司 | 2021-05-14 | — | — | CN | disclosed |
| EP-2590968-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | Novartis AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |