Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 4/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | SHBG | P04278 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | CCKBR | P32239 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193479 | 1.00 | ESR1 (0.60) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL11866439 | 0.81 | SLC6A4 (0.61) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL29395842 | 0.81 | ESR1 (0.41) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL16421288 | 0.80 | PGR (0.76) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL20851703 | 0.78 | ESR1 (0.57) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL20851686 | 0.78 | ESR1 (0.55) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL20851704 | 0.78 | ESR1 (0.55) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL6689499 | 0.78 | ESR1 (0.55) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL28719362 | 0.78 | ESR1 (0.57) | ESR1PGRCHRM2SLC6A2SLC6A4 | |
| SCHEMBL8675862 | 0.77 | PGR (0.67) | ESR1PGRCHRM2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7667056-B2 | Desogestrel synthesis characterized by regioselective reduction of a diketo intermediate 18-methyl-11-hydroxyestr-4-en-3,17-dione; higher yields, easier purification | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 2010-02-23 | — | — | US | disclosed |
| EP-1525214-B1 | PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF STEROIDS WITH A PROGESTOGEN ACTIVITY | POLI IND CHIMICA SPA (IT) | 2006-12-27 | — | — | EP | disclosed |
| US-20050234251-A1 | Process and new intermediates for the preparation of steroids with a progestogen activity | POLI INDUSTRIA CHEMICA SPA (IT) | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234251-A1 | Process and new intermediates for the preparation of steroids with a progestogen activity | CYP19A1, CYP17A1, CYP21A2 | ESR1 115/4885PGR 12/4885CHRM2 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.