Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851704 | 1.00 | ESR1 (0.55) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL20851686 | 1.00 | ESR1 (0.55) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL20851607 | 0.89 | ESR1 (0.45) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL8410551 | 0.89 | ESR1 (0.45) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL20851698 | 0.83 | PGR (0.57) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL14946855 | 0.83 | PGR (0.57) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL9194138 | 0.83 | PGR (0.57) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL9547849 | 0.83 | ESR1 (0.50) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL14946875 | 0.82 | SHBG (0.41) | ESR1PGRARCHRM2SLC6A2 | |
| SCHEMBL11150692 | 0.81 | ESR1 (0.49) | ESR1PGRARCHRM2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057819-A | Method for recovering desogestrel recrystallization mother liquor | 上海共拓医药化工有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-114057819-A | Method for recovering desogestrel recrystallization mother liquor | 上海共拓医药化工有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-7667056-B2 | Desogestrel synthesis characterized by regioselective reduction of a diketo intermediate 18-methyl-11-hydroxyestr-4-en-3,17-dione; higher yields, easier purification | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 2010-02-23 | — | — | US | disclosed |
| US-7667056-B2 | Desogestrel synthesis characterized by regioselective reduction of a diketo intermediate 18-methyl-11-hydroxyestr-4-en-3,17-dione; higher yields, easier purification | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 2010-02-23 | — | — | US | disclosed |
| WO-2009033499-A1 | TOTAL SYNTHESIS OF ENANTIOPURE DESOGESTREL | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts (DE) | 2009-03-19 | — | — | WO | disclosed |
| WO-2004101594-A1 | NEW MONO-AND BISMETHYLENE-STEROID DERIVATIVES AND PROCESS FOR THEIR SYNTHESIS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2004-11-25 | — | — | WO | disclosed |
| EP-0643070-B1 | Steroid intermediates and process for their preparation | JENAPHARM GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5831104-A | Steroid intermediate products and method of their production | JENAPHARM GMBH (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0643070-A1 | Steroid intermediates and process for their preparation | JENAPHARM GmbH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0440752-B1 | METHOD FOR THE PREPARATION OF 3-DESOXY-4-ENE STEROIDS | SCHERING AG (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5140106-A | PROCESS FOR THE PRODUCTION OF 3-DEOXY-4-ENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-08-18 | — | — | US | disclosed |
| EP-0440752-A1 | METHOD FOR THE PREPARATION OF 3-DESOXY-4-ENE STEROIDS. | SCHERING AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| WO-1990011290-A1 | METHOD FOR THE PREPARATION OF 3-DESOXY-4-ENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| US-4277468-A | CONTRACEPTIVES, PROGESTATIONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |