Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 15/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
| ▸ | HK2 | P52789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194078 | 1.00 | TYMP (0.49) | TYMPKIF11ADORA1HK1HK2 | |
| SCHEMBL23113802 | 1.00 | TYMP (0.49) | TYMPKIF11ADORA1HK1HK2 | |
| SCHEMBL2456078 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL8158736 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL22033901 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL15536591 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL2456082 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL8158741 | 0.98 | TYMP (0.48) | TYMPKIF11 | |
| SCHEMBL5443832 | 0.92 | TYMP (0.52) | TYMPKIF11ADORA1 | |
| SCHEMBL10408396 | 0.92 | TYMP (0.52) | TYMPKIF11ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061519-B1 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | SIEMENS MEDICAL SOLUTIONS (US) | 2016-03-30 | — | — | EP | disclosed |
| US-7666392-B2 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| EP-2061519-A2 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | Siemens Medical Solutions USA, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-07-17 | — | — | US | disclosed |
| WO-2008033561-A2 | CLICK CHEMISTRY-DERIVED CYCLOPEPTIDE DERIVATIVES AS IMAGING AGENTS FOR INTEGRINS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| US-4021542-A | Derivatives of hydrazino-monosaccharides and aldohexoses which are useful as intermediates for preparing compounds or as compounds which lower the uric acid | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080170992-A1 | Click chemistry-derived cyclopeptide derivatives as imaging agents for integrins | ITGB3, VCAM1, ITGB1 | TYMP 1990/4885KIF11 3041/4885ADORA1 2590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.