SCHEMBL319418

SCHEMBL319418

Cc1cccc2c1C=CC2

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
HTR5A P47898 1/20 0.32
HTR2C P28335 1/20 0.31
TRPA1 O75762 2/20 0.30
CD44 P16070 1/20 0.30
ALOX12 P18054 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454972 0.98 CA1 (0.35) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL5344967 0.82 MYC (0.37) CA1CA2CA7CA9HTR5A
SCHEMBL5344329 0.82 HTR7 (0.38) CYP1A2ALDH1A1CA1CA2HPGD
SCHEMBL29767630 0.82 HTR7 (0.38) CYP1A2ALDH1A1CA1CA2HPGD
SCHEMBL28424456 0.81 HTR7 (0.37) CYP1A2ALDH1A1CA1CA2HPGD
SCHEMBL5344283 0.81 CNR2 (0.33) ALDH1A1HPGDSMN1; SMN2TRPA1ATM
SCHEMBL1923295 0.80 CYP1A2 (0.33) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL19390301 0.78 ACHE (0.33) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL10357346 0.77 TSHR (0.41) CYP2A6CYP1A2ALDH1A1HPGDTSHR
SCHEMBL6649235 0.75 MYC (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10030131-B2 Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-24 US claimed
US-9914328-B2 Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) 2018-03-13 US claimed
CN-104271360-B Pneumatic object provided with a gastight layer based on a thermoplastic elastomer and a lamellar filler 米其林集团总公司 2016-12-14 CN claimed
EP-2844500-B1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER BASED ON A THERMOPLASTIC ELASTOMER AND ON A LAMELLAR FILLER MICHELIN & CIE (FR) 2016-03-23 EP claimed
CN-103228462-B The inflatable articles of the impermeable layer of the gas with the blend based on butyl rubber and thermoplastic elastomer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-11-25 CN claimed
EP-2569173-B1 PNEUMATIQUE OBJECT PROVIDED WITH A GAS TIGHT LAYER BASED ON A THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC MICHELIN & CIE (FR) 2015-10-21 EP claimed
CN-102939210-B Inflatable article having a gas-tight layer comprising a thermoplastic elastomer and a thermoplastic and process for making a gas-tight elastomer composition MICHELIN SOC TECH 2015-07-22 CN claimed
EP-2590825-B1 INFLATABLE ARTICLE PROVIDED WITH GAS-IMPERMEABLE LAYER BASED ON A BLEND OF A BUTYL RUBBER AND A THERMOPLASTIC ELASTOMER MICHELIN & CIE (FR) 2015-03-25 EP claimed
US-20150079323-A1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER BASED ON A THERMOPLASTIC ELASTOMER AND ON A LAMELLAR FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2015-03-19 US claimed
EP-2844500-A1 PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER BASED ON A THERMOPLASTIC ELASTOMER AND ON A LAMELLAR FILLER Compagnie Générale des Etablissements Michelin (FR) 2015-03-11 EP claimed
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed
US-5824618-A TITANIUM COMPOUND, GROUP 1-3 COMPOUND, ORGANOCYCLIC COMPOUND NIPPON OIL CO., LTD. (JP) 1998-10-20 US claimed
US-5795839-A COORDINATION POLYMERIZATION CATALYST FOR POLYOLEFIN MANUFACTURE NIPPON OIL CO., LTD. (JP) 1998-08-18 US claimed
US-5707914-A ZIRCONIUM OR HAFNIUM ALKYLS OR ALKOXIDES NIPPON OIL CO., LTD. (JP) 1998-01-13 US claimed
US-5677401-A COORDINATION CATALYST NIPPON OIL CO., LTD. (JP) 1997-10-14 US claimed
US-5670588-A TITANIUM, ZIRCONIUM, OR HAFNIUM COMPOUND, ORGANOCYCLIC HYDROCARBON OR SIICON COMPOUND, MODIFIED ORGANOALUMINUM COMPOUND NIPPON OIL CO., LTD. (JP) 1997-09-23 US claimed
US-5643845-A HAFNIUM OR ZIRCONIUM COMPOUND AND A CYCLOPENTADIENE OR INDENE COMPOUND, HIGH MOLECULAR WEIGHT NIPPON OIL CO., LTD. (JP) 1997-07-01 US claimed
US-5625014-A Method for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1997-04-29 US claimed
US-5594082-A COORDINATION CATALYST, ALUMOXANE, CYCLOPENTADIENE, INDENE, AZULENE OR FLUORENE COMPOUND NIPPON OIL CO., LTD. (JP) 1997-01-14 US claimed
US-5451555-A Catalyst components for polymerization of olefins NIPPON OIL CO., LTD. (JP) 1995-09-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 CYP2A6 284/4885CYP1A2 87/4885ALDH1A1 1723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.