Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31880 | 0.91 | PPARD (0.54) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31763 | 0.88 | PPARA (0.45) | PPARAPPARDPPARGHDAC6 | |
| SCHEMBL31881 | 0.84 | PTGER4 (0.51) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL12634671 | 0.77 | PPARA (0.55) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31944 | 0.76 | PPARA (0.47) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31954 | 0.76 | PPARA (0.54) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL12636568 | 0.76 | PTGER4 (0.52) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31949 | 0.75 | PPARA (0.55) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31948 | 0.74 | PPARA (0.58) | PTGER4PTGER2PPARAPPARDPPARG | |
| SCHEMBL31889 | 0.73 | PPARA (0.51) | PTGER4PTGER2PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |