Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.58 |
| ▸ | PPARD | Q03181 | 4/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31881 | 0.90 | PTGER4 (0.51) | PPARAPPARDPPARGPTGER4PTGER2 | |
| SCHEMBL31944 | 0.89 | PPARA (0.47) | PPARAPPARDPPARGPTGER4PTGER2 | |
| SCHEMBL31954 | 0.84 | PPARA (0.54) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31880 | 0.84 | PPARD (0.54) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12634630 | 0.83 | PPARA (0.59) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31929 | 0.82 | PDE4A (0.44) | PPARAPPARDPPARGLIPGALDH1A1 | |
| SCHEMBL31949 | 0.82 | PPARA (0.55) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31940 | 0.82 | PPARA (0.58) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31932 | 0.82 | PDE4A (0.44) | PPARAPPARDPPARGLIPGALDH1A1 | |
| SCHEMBL31970 | 0.81 | PDE4A (0.43) | PPARAPPARDPPARGLIPGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |