Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31949 | 0.92 | PPARA (0.55) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31943 | 0.89 | PPARG (0.50) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31889 | 0.88 | PPARA (0.51) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31880 | 0.85 | PPARD (0.54) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL31948 | 0.84 | PPARA (0.58) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12636546 | 0.81 | PPARA (0.61) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12636184 | 0.81 | PPARA (0.59) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12634669 | 0.78 | PPARA (0.61) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12634655 | 0.78 | PPARA (0.58) | PPARAPPARDPPARGLIPGPTGER4 | |
| SCHEMBL12634663 | 0.78 | PPARA (0.60) | PPARAPPARDPPARGLIPGPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |