SCHEMBL3194458

CC(C)C[C@@H]([C]=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)[C@@H](C)O

nearest known ligand 0.43

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	7/20	0.39

▸	PTPN1	P18031	2/20	0.35

▸	REN	P00797	1/20	0.35

▸	EGFR	P00533	1/20	0.34

▸	BACE2	Q9Y5Z0	1/20	0.34

▸	NPY5R	Q15761	3/20	0.34

▸	NPY1R	P25929	2/20	0.34

▸	NPY4R	P50391	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3070832	0.91	MMP2 (0.37)	BACE1REN
SCHEMBL16468394	0.80	BACE1 (0.45)	BACE1EGFRBACE2
SCHEMBL2108028	0.80	MMP2 (0.37)	—
SCHEMBL2108033	0.80	MMP2 (0.37)	—
SCHEMBL30883239	0.79	EGFR (0.41)	BACE1RENEGFR
SCHEMBL30596285	0.78	FOLH1 (0.53)	BACE1
SCHEMBL2638573	0.78	DPP4 (0.42)	—
SCHEMBL2638527	0.78	DPP4 (0.42)	—
SCHEMBL2638683	0.78	DPP4 (0.42)	—
SCHEMBL2637830	0.78	DPP4 (0.42)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100047762-A1	METHOD TO MONITOR DRUG EFFICACY IN DIABETIC PATIENTS USING AN ASSAY FOR 1,5-ANHYDRO-D-GLUCITOL	NIPPON KAYAKU KABUSHIKI KAISHA (JP)	2010-02-25	—	—	US	disclosed