Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194458 | 0.91 | BACE1 (0.39) | BACE1REN | |
| SCHEMBL2108033 | 0.88 | MMP2 (0.37) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL2108028 | 0.88 | MMP2 (0.37) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL30683244 | 0.80 | ALDH1A1 (0.42) | MMP2MMP9MMP8BACE1LAP3 | |
| SCHEMBL2184616 | 0.80 | MMP2 (0.39) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL28082201 | 0.80 | MMP2 (0.39) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL11568997 | 0.80 | PSMB11 (0.34) | BACE1CTSC | |
| SCHEMBL11568991 | 0.80 | PSMB11 (0.34) | BACE1CTSC | |
| SCHEMBL1795666 | 0.79 | SLC7A5 (0.40) | CTSC | |
| SCHEMBL8863575 | 0.79 | SLC7A5 (0.40) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |