Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151179 | 0.84 | KMT2A (0.48) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL27681062 | 0.84 | IDO1 (0.51) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL4624627 | 0.81 | IDO1 (0.50) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL1368372 | 0.80 | IDO1 (0.59) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL453906 | 0.80 | MAPT (0.47) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL29442601 | 0.80 | MAPT (0.47) | MAPTTP53GAAHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL25292962 | 0.79 | IDO1 (0.48) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL1953525 | 0.79 | IDO1 (0.48) | MAPTTP53GAAHSD17B10MAPK1 | |
| SCHEMBL1122539 | 0.78 | MAPT (0.53) | MAPTTP53GAAHSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL28211867 | 0.78 | IDO1 (0.57) | MAPTTP53GAAHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
| EP-3833401-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | Oregon Health & Science University (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-3829420-A2 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | Oregon Health & Science University (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2020033435-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020033435-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020023911-A2 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2020-01-30 | — | — | WO | disclosed |
| US-20140255920-A1 | RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-8754244-B1 | Rhodamine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-06-17 | — | — | US | disclosed |
| US-8455413-B2 | Additive for oils and lubricant comprising the same | KH NEOCHEM CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100031453-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT | L'OREAL S.A. (FR) | 2010-02-11 | — | — | US | disclosed |
| EP-2032540-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT | L'Oreal (FR) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008034650-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT | L'OREAL (FR) | 2008-03-27 | — | — | WO | disclosed |
| CN-1332942-C | Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-22 | — | — | CN | disclosed |
| CN-1703397-A | Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2005-11-30 | — | — | CN | disclosed |
| US-5696190-A | CURABLE ELASTOMERS MIXED WITH AN ACID SALT OF (DI)ALKYLAMINOALKYL PHENOL | SARTOMER COMPANY (US) | 1997-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | MAPT 636/4885TP53 869/4885GAA 4341/4885 |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | NCOA2, NCOR2, NR1H2 | MAPT 4173/4885TP53 4603/4885GAA 4788/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | MAPT 1093/4885TP53 3690/4885GAA 1341/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | MAPT 803/4885TP53 532/4885GAA 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.