Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31932 | 0.92 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPPARA | |
| SCHEMBL31929 | 0.89 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DPPARA | |
| SCHEMBL31948 | 0.81 | PPARA (0.58) | PPARAPPARDLIPGKMT2APOLB | |
| SCHEMBL31881 | 0.80 | PTGER4 (0.51) | PPARAPPARDPPARG | |
| SCHEMBL31944 | 0.79 | PPARA (0.47) | PDE4APDE4BPDE4CPDE4DPPARA | |
| SCHEMBL31947 | 0.73 | LMNA (0.44) | MEN1KMT2APOLBMAPT | |
| SCHEMBL31703 | 0.72 | MRGPRX4 (0.47) | MEN1KMT2AMAPT | |
| SCHEMBL31880 | 0.69 | PPARD (0.54) | PPARAPPARDLIPGPOLBPPARG | |
| SCHEMBL31942 | 0.68 | PTGER4 (0.47) | PDE4APDE4BPDE4CPDE4DPPARA | |
| SCHEMBL9165337 | 0.68 | LMNA (0.54) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |